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Deep Anterior Lamellar Keratoplasty: Current Status and Future Directions
Cornea ( IF 1.9 ) Pub Date : 2022-05-01 , DOI: 10.1097/ico.0000000000002840
Angeli Christy Yu 1, 2, 3 , Rossella Spena 1, 2, 3 , Marco Pellegrini 1, 2, 3 , Cristina Bovone 1, 2, 3 , Massimo Busin 1, 2, 3
Affiliation  

Deep anterior lamellar keratoplasty (DALK) involves selective replacement of diseased corneal stroma while preserving normal healthy endothelium. Despite several well-recognized advantages, the uptake of DALK has remained sluggish with an adoption rate that has plateaued over the past decade. Misconceptions such as the rarity of complications of penetrating keratoplasty, lack of standardization of the DALK technique, and limited substantial benefit in visual and refractive outcomes are frequently cited as arguments against performing DALK. This brief review discusses the recent findings that refute these perceived barriers; describes contemporary techniques, tools, and modifications in the surgical approach; and evaluates the evidence regarding the clinical outcomes of DALK.



中文翻译:

深前板层角膜移植术:现状和未来方向

深前板层角膜移植术 (DALK) 涉及选择性替换患病的角膜基质,同时保留正常健康的内皮。尽管有一些众所周知的优势,但 DALK 的采用率仍然低迷,在过去十年中采用率已趋于稳定。诸如穿透性角膜移植术并发症罕见、DALK 技术缺乏标准化以及视觉和屈光结果的实质性益处有限等误解经常被引用作为反对执行 DALK 的论据。这篇简短的评论讨论了最近的发现,驳斥了这些感知到的障碍;描述手术方法的当代技术、工具和改进;并评估有关 DALK 临床结果的证据。

更新日期:2022-05-01
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