Maternal vaccination is an effective means of protecting pregnant women, their fetuses, and infants from vaccine-preventable infections. Despite the availability of sufficient safety data to support the use of vaccines during pregnancy, maternal immunization remains an underutilized method of disease prevention, often because of concerns from both healthcare providers and pregnant women about vaccine safety. Such concerns have been reflected in the low uptake of the COVID-19 vaccine among pregnant women seen in many parts of the world. Here, we present an update of the current recommendations for the use of vaccines during pregnancy, including the evidence supporting the use of novel vaccine platforms. We also provide an overview of the data supporting the use of COVID-19 vaccines in pregnancy and an update of the status of vaccines that are currently under development for use in pregnant women.

孕产妇疫苗接种是保护孕妇及其胎儿和婴儿免受疫苗可预防感染的有效手段。尽管有足够的安全数据支持怀孕期间使用疫苗，但孕产妇免疫仍然是一种未得到充分利用的疾病预防方法，这通常是因为医疗保健提供者和孕妇对疫苗安全性的担忧。这种担忧反映在世界许多地区孕妇对 COVID-19 疫苗的接种率较低上。在这里，我们介绍了当前怀孕期间使用疫苗的建议的更新，包括支持使用新型疫苗平台的证据。我们还概述了支持在怀孕期间使用 COVID-19 疫苗的数据，以及目前正在开发的用于孕妇的疫苗的最新状态。