Background

Organosilanes have been massively implemented as building blocks in the fields of sol–gel material synthesis, surface functionalization, and nanotechnology. However, organosilane has been humbled by limitations, such as poor reproducibility, fast hydrolysis and heterogeneous molecular orientation. An emerging silatrane is gaining tremendous interest due to the unique tricyclic caged structure and transannular N→Si dative bond to provide chemical stability in aqueous solution and controllable deposition on surfaces.

Methods

Aminopropyl silatrane (APS), Mercaptopropyl silatrane (MPS) and 3-Mercaptopropyl trimethoxysilane (MPTMS) were applied to modification of silicon oxide substrates to in-situ graft hydrophilic polymers and immobilize gold nanoparticles (AuNPs). Thin and uniform silatrane coatings have been proved by atomic force spectroscopy, ellipsometry and X-ray photoelectron spectroscopy.

Significant Findings

Antifouling poly(ethylene glycol) methacrylate (PEGMA) was grafted separately on MPS and MPTMS via surface-initiated thiol-ene photopolymerization. We found that MPS-PEGMA films were 30% superior to MPTMS-PEGMA films in protein repellency. Moreover, APS and MPS were co-deposited to attract and conjugate gold nanoparticles. AuNPs cluster size on APS films was found to increase 3.43 times along with broader AuNPs absorbance peaks after acid treatment, whereas cluster size increased only 4% on mixed silatrane-modified films. These discoveries are pertinent to robust and versatile properties that silatrane offers.

中文翻译：

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用于金纳米颗粒原位聚合和固定的多功能硫醇和氨基官能化硅烷

背景

有机硅烷在溶胶-凝胶材料合成、表面功能化和纳米技术领域已被大规模应用为构件。然而，有机硅烷受到了一些限制，如重现性差、水解快和分子取向不均匀。由于独特的三环笼状结构和跨环状 N→Si 配位键在水溶液中提供化学稳定性和在表面上的可控沉积，新兴的 Silatrane 引起了极大的兴趣。

方法

氨基丙基硅烷 (APS)、巯基丙基硅烷 (MPS) 和 3-巯基丙基三甲氧基硅烷 (MPTMS) 用于将氧化硅基材改性为原位接枝亲水聚合物和固定金纳米粒子 (AuNPs)。原子力光谱、椭偏仪和 X 射线光电子能谱已证明薄而均匀的 Silatrane 涂层。

重要发现

防污聚（乙二醇）甲基丙烯酸酯（PEGMA）通过表面引发的硫醇-烯光聚合分别接枝在 MPS 和 MPTMS 上。我们发现 MPS-PEGMA 薄膜在蛋白质排斥性方面优于 MPTMS-PEGMA 薄膜 30%。此外，APS 和 MPS 被共同沉积以吸引和结合金纳米粒子。发现 APS 薄膜上的 AuNPs 簇大小在酸处理后随着更宽的 AuNPs 吸收峰增加了 3.43 倍，而在混合 silatrane 改性薄膜上簇大小仅增加了 4%。这些发现与 Silatrane 提供的强大和多功能特性有关。