PURPOSE To assess the impact of the use of artificial tears during the preoperative work-up performed before age-related cataract surgery, when a toric intraocular lens (IOL) was indicated. METHODS This was a monocentric prospective study assessing 73 eyes of 51 patients, included consecutively after a preoperative work-up performed without artificial tears (no artificial tears group), when a toric IOL was indicated. Each included patient underwent a second series of examinations: biometry using the IOLMaster 700 (Carl Zeiss Meditec AG) and topography using the OPD-Scan II (Nidek), 1 minute after artificial tears instillation (artificial tears group; hyaluronate de sodium 0.15%, threalose 3% [Théalose; Théa]). Changes in anterior corneal astigmatism and subsequent changes in toric IOL calculation were analyzed. The error in predicted residual astigmatism was calculated. RESULTS Anterior corneal astigmatism and total corneal astigmatism measured with the IOLMaster 700 were significantly modified when artificial tears were instilled before the examinations (1.51 ± 0.57 diopters [D], range: 0.75 to -3.55 vs 1.42 ± 0.63 D, range: 0.42 to 3.35 D; P = .043 and 1.59 ± 0.54 D, range: 0.87 to 3.48 vs 1.51 ± 0.59 D, range: 0.56 to 3.27 D, P = .038, respectively). This modification led to a change in IOL cylinder calculation in 43.8% of cases and to a change in implantation axis greater than 10° in 17.7% of cases. These changes were significantly greater in patients with a breakup time (BUT) less than 5 seconds (57.5% and 27.8%, with P = .009 and .029, respectively). In the subgroup of patients with a BUT of less than 5 seconds, the mean absolute error in predicted astigmatism was significantly lower after artificial tears instillation (0.48 ± 0.50 D, range: 0.00 to 2.79 vs 0.37 ± 0.25 D, range: 0.00 to 1.10 D, P = .048). CONCLUSIONS Dry eye significantly impacted toric IOL calculations and should be taken into account during the preoperative assessments. Using artificial tears reduced the number of refractive errors. [J Refract Surg. 2021;37(11):759-766.].

中文翻译：

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年龄相关性白内障手术前环面人工晶状体的术前评估是否应使用人工泪液？TORIDE 研究。

目的 评估在年龄相关性白内障手术前进行的术前检查期间使用人工泪液的影响，此时需要使用环面人工晶状体 (IOL)。方法 这是一项单中心前瞻性研究，评估了 51 名患者的 73 只眼，包括在没有人工泪液的情况下（无人工泪液组）进行的术前检查后，当需要使用环面人工晶状体时连续纳入。在人工泪液滴注后 1 分钟（人工泪液组；透明质酸钠 0.15%，海藻糖 3% [Théalose; Théa])。分析了前角膜散光的变化和随后环面 IOL 计算的变化。计算预测的残余散光的误差。结果在检查前滴入人工泪液时，使用 IOLMaster 700 测量的前角膜散光和总角膜散光显着改变（1.51 ± 0.57 屈光度 [D]，范围：0.75 至 -3.55 vs 1.42 ± 0.63 D，范围：0.352） D；P = .043 和 1.59 ± 0.54 D，范围：0.87 至 3.48 与 1.51 ± 0.59 D，范围：0.56 至 3.27 D，P = .038，分别）。这一修改导致 43.8% 的情况下 IOL 柱面计算发生变化，17.7% 的情况下植入轴的变化大于 10°。这些变化在分手时间 (BUT) 小于 5 秒的患者中明显更大（分别为 57.5% 和 27.8%，P = .009 和 .029）。在 BUT 小于 5 秒的患者亚组中，人工泪液滴注后预测散光的平均绝对误差显着降低（0.48 ± 0.50 D，范围：0.00 至 2.79 vs 0.37 ± 0.25 D，范围：0.00 至 1.10 D，P = .048）。结论 干眼显着影响环面 IOL 计算，应在术前评估中予以考虑。使用人工泪液减少了屈光不正的数量。[J 屈光手术。2021;37(11):759-766.]。