IL-6–induced cGGNBP2 encodes a protein to promote cell growth and metastasis in intrahepatic cholangiocarcinoma,Hepatology

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IL-6–induced cGGNBP2 encodes a protein to promote cell growth and metastasis in intrahepatic cholangiocarcinoma
Hepatology ( IF 12.9 ) Pub Date : 2021-11-10 , DOI: 10.1002/hep.32232
Hui Li _{1,

2,

3} , Tian Lan _{1,

2} , Hailing Liu _{1,

2} , Chang Liu ₁ , Junlong Dai ₁ , Lin Xu ₂ , Yunshi Cai _{1,

2} , Guimin Hou _{1,

2} , Kunlin Xie _{1,

2} , Mingheng Liao _{1,

2} , Jiaxin Li _{1,

2} , Jiwei Huang _{1,

2} , Kefei Yuan _{1,

2} , Genshu Wang ₄ , Yong Zeng _{1,

2} , Hong Wu _{1,

2}

Affiliation

IL-6–induced tumor progression has been well established through the induction of antiapoptotic and proliferative genes. However, whether other mechanisms such as IL-6 regulation of circular RNAs (circRNAs) may also contribute to tumor development remains unknown.

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