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Hygromycin A in the Lymelight
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2021-11-10 , DOI: 10.1016/j.chom.2021.10.007 Paul Michael Arnaboldi 1 , Sukanya Narasimhan 2
中文翻译:
Lymelight 中的潮霉素 A
更新日期:2021-11-10
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2021-11-10 , DOI: 10.1016/j.chom.2021.10.007 Paul Michael Arnaboldi 1 , Sukanya Narasimhan 2
Affiliation
Lyme disease, which is caused by the spirochete Borrelia burgdorferi, is on the rise. Current treatment relies on broad-spectrum antibiotics that perturb the gut microbiome. In a recent paper in Cell, Leimer et al. demonstrate the utility of a long-forgotten antibiotic, Hygromycin A, as a spirochete-specific antibacterial that is conducive to gut health.
中文翻译:
Lymelight 中的潮霉素 A
由螺旋体伯氏疏螺旋体引起的莱姆病呈上升趋势。目前的治疗依赖于干扰肠道微生物群的广谱抗生素。在最近发表在Cell上的一篇论文中,Leimer 等人。证明了一种长期被遗忘的抗生素潮霉素 A 的效用,它是一种有益于肠道健康的螺旋体特异性抗菌剂。