Individuals with suspected COVID-19 symptoms (n=202) were tested using nasopharyngeal RT-qPCR. All individuals underwent corneal esthesiometry measurements using the Cochet-Bonnet esthesiometer during their first visit; 50 participants underwent an additional measurement at a mean interval of 32.5 (17.8) days. COVID-19 was confirmed in 101 subjects (50%) using nasopharyngeal PCR. The mean time from symptom onset to disease diagnosis and corneal esthesiometry was 4.2 (2.1) days. Mean corneal esthesiometry findings based on the positive and negative PCR status indicated no statistical difference. This study demonstrated that COVID-19 had no effect on corneal esthesiometry in individuals with acute-phase COVID-19.

中文翻译：

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COVID-19 对角膜感觉测量的影响

使用鼻咽 RT-qPCR 对疑似 COVID-19 症状的个体 (n=202) 进行了测试。所有个体在第一次访问期间都使用 Cochet-Bonnet 感觉仪进行了角膜感觉仪测量；50 名参与者以 32.5 (17.8) 天的平均间隔接受了额外的测量。使用鼻咽 PCR 在 101 名受试者 (50%) 中确认了 COVID-19。从症状出现到疾病诊断和角膜感觉测量的平均时间为 4.2 (2.1) 天。基于阳性和阴性 PCR 状态的平均角膜感觉测量结果表明没有统计学差异。这项研究表明，COVID-19 对急性期 COVID-19 患者的角膜感觉测量没有影响。