Construction of 6H-benzo[c]thiochromenes via a tandem reaction of arynes with thionoesters,Organic Chemistry Frontiers

当前位置： X-MOL 学术 › Org. Chem. Front. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Construction of 6H-benzo[c]thiochromenes via a tandem reaction of arynes with thionoesters
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2021-11-10 , DOI: 10.1039/d1qo01177d
Yi An ₁ , Fang Zhang ₁ , Guangfen Du ₁ , Zhihua Cai ₁ , Lin He ₁

Affiliation

A mild and transition-metal free tandem reaction for the construction of 6H-benzo[c]thiochromenes has been developed. Thionoesters react with two molecules of arynes through a Diels–Alder cycloaddition/nucleophilic arylation process to afford 6-alkoxy-6-aryl-6H-benzo[c]thiochromenes in 37–80% yields. In addition, the Diels–Alder cycloaddition/aromatization tandem reaction of thionoesters with one molecule of aryne provides the construction of 6-alkoxyl-6H-benzo[c]thiochromenes in 51–75% yields.

中文翻译：

通过芳烃与硫酮酯的串联反应构建 6H-苯并[c] 硫代色烯

已开发出一种温和且无过渡金属的串联反应，用于构建 6 H-苯并[ c ] 硫色素烯。硫代酯通过狄尔斯-阿尔德环加成/亲核芳基化过程与两分子芳烃反应，以 37-80% 的产率得到 6-烷氧基-6-芳基-6 H-苯并[ c ] 硫色烯。此外，硫酮酯与一分子芳烃的 Diels-Alder 环加成/芳构化串联反应以 51-75% 的产率构建了 6-alkoxyl-6 H -benzo [ c ]thiochromenes。

更新日期：2021-11-10

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11