The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We describe and evaluate an Early Warning, Alert and Response System (EWARS) implemented in the Beni health zone of DRC during August 5, 2018–June 30, 2020. During this period, 194,768 alerts were received, of which 30,728 (15.8%) were validated as suspected cases. From these, 801 confirmed and 3 probable cases were detected. EWARS showed an overall good performance: sensitivity and specificity >80%, nearly all (97%) of alerts investigated within 2 hours of notification, and good demographic representativeness. The average cost of the system was US $438/case detected and US$1.8/alert received. The system was stable, despite occasional disruptions caused by political insecurity. Our results demonstrate that EWARS was a cost-effective component of the Ebola surveillance strategy in this setting.

刚果民主共和国 (DRC) 第 10 次也是最大的埃博拉病毒病疫情于 2018 年 8 月在北基伍省宣布，并于 2020 年 6 月结束。我们描述并评估了在2018 年 8 月 5 日至 2020 年 6 月 30 日期间，刚果民主共和国贝尼卫生区收到了 194,768 次警报，其中 30,728 次（15.8%）被确认为疑似病例。其中，确诊病例801例，疑似病例3例。EWARS 显示出整体良好的性能：灵敏度和特异性 >80%，在通知后 2 小时内调查的几乎所有警报 (97%)，以及良好的人口统计学代表性。该系统的平均成本为 438 美元/检测到的案例和 1.8 美元/收到的警报。尽管偶尔会因政治不安全而造成中断，但该系统仍是稳定的。