Purpose: 

The purpose of this study was to assess the medical history of adenoviral keratoconjunctivitis (AK) and subepithelial infiltrates (SEIs) among French ophthalmologists and orthoptists and the frequency of unreported occupational diseases. We also described short-term and long-term consequences of AK and evaluated associated factors.

Methods: 

The REDCap questionnaire was diffused online several times over 7 consecutive months, from October 2019 to May 2020, through mailing lists (French Society of Ophthalmology, residents, and hospital departments), social networks, and by word of mouth.

Results: 

Seven hundred ten participants were included with a response rate of 6.2% for ophthalmologists, 3.8% for orthoptists, and 28.3% for ophthalmology residents. The medical history of AK was found in 24.1% (95% confidence interval 21%–27.2%) of respondents and SEI in 43.9% (36.5%–51.3%) of the AK population. In total, 87.1% (82.1%–92.1%) of AK occupational diseases were not declared. In total, 57.7% of respondents took 9.4 ± 6.2 days of sick leave, mostly unofficial, and 95.7% stopped surgeries for 13.0 ± 6.6 days. Among the AK population, 39.8% had current sequelae, with 17.5% having persistent SEIs, 19.9% using current therapy, and 16.4% experiencing continuing discomfort. SEIs were associated with wearing contact lenses (odds ratio 3.31, 95% confidence interval 1.19–9.21) and smoking (4.07, 1.30–12.8). Corticosteroid therapy was associated with a greater number of sequelae (3.84, 1.51–9.75).

Conclusions: 

AK and SEI affect a large proportion of ophthalmologists and orthoptists, possibly for years, with high morbidity leading to occupational discomfort. Few practitioners asked for either to be recognized as an occupational disease. Associated factors would require a dedicated study.

中文翻译：

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眼科医生和视力矫正师腺病毒性角结膜炎的并发症：流行病学和危险因素，回顾性问卷分析

目的： 

本研究的目的是评估法国眼科医生和视力矫正师的腺病毒性角结膜炎（AK）和上皮下浸润（SEIs）病史以及未报告的职业病的频率。我们还描述了 AK 的短期和长期后果并评估了相关因素。

方法： 

从 2019 年 10 月到 2020 年 5 月，REDCap 调查问卷在连续 7 个月内通过邮件列表（法国眼科学会、住院医师和医院部门）、社交网络和口碑在网上多次传播。

结果： 

共有 710 名参与者参与其中，眼科医生的响应率为 6.2%，视力矫正师的响应率为 3.8%，眼科住院医师的响应率为 28.3%。24.1%（95%置信区间 21%–27.2%）的受访者有 AK 病史，43.9%（36.5%–51.3%）的 AK 人群有 SEI 病史。总共有 87.1%（82.1%–92.1%）的 AK 职业病未申报。总体而言，57.7% 的受访者请了 9.4 ± 6.2 天的病假（大部分是非官方病假），95.7% 的受访者停止手术 13.0 ± 6.6 天。在 AK 人群中，39.8% 的人目前有后遗症，其中 17.5% 的人有持续性 SEI，19.9% 的人正在使用当前的治疗，16.4% 的人经历持续的不适。SEI 与佩戴隐形眼镜（比值比 3.31，95% 置信区间 1.19–9.21）和吸烟（4.07，1.30–12.8）相关。皮质类固醇治疗与更多的后遗症相关（3.84，1.51-9.75）。

结论： 

AK 和 SEI 影响很大一部分眼科医生和视力矫正师，可能持续数年，发病率高，导致职业不适。很少有从业者要求将这两种疾病认定为职业病。相关因素需要专门研究。