A comparative analysis is formed to analyze the combined effects of a binary chemical reaction and activation energy in the flow of bio-nanofluid due to the thin moving needle using the mathematical nanofluid model offered by Buongiorno with different boundary conditions namely, Newtonian heating and prescribed surface temperature. The governing partial differential equations converted into a set of final controlled governing physical flow equations by using similarity variables and then solved numerically by Runge–Kutta–Fehlberg method along with shooting technique and analytically by differential transform method. The results gained for the dimensionless velocity, temperature, concentration, motile diffusivity number, Nusselt number and Sherwood number are presented through graphs and tables. The present study reveals that an enhancement in the pertinent parameters has considerably altered the physical characteristics of the flow and heat transfer, which applies in biosensors and biomedical instrumentation. Also, the rate of heat transfer from the needle to the fluid is controlled by applying Newtonian heating than by applying prescribed surface temperature against all the parameters. In addition, we carried out the statistical analysis to determine the dependence of the physical parameter on the rate of heat transfer for both cases of heating process.

使用Buongiorno提供的不同边界条件即牛顿加热和指定表面的数学纳米流体模型，形成对比分析，分析由于细动针引起的生物纳米流体流动中的二元化学反应和活化能的综合影响温度。利用相似变量将控制偏微分方程转化为一组最终受控的控制物理流动方程，然后通过Runge-Kutta-Fehlberg方法结合射击技术进行数值求解，并通过微分变换方法进行解析。获得的无量纲速度、温度、浓度、运动扩散系数、努塞尔数和舍伍德数的结果通过图表和表格呈现。目前的研究表明，相关参数的增强大大改变了流动和传热的物理特性，这适用于生物传感器和生物医学仪器。此外，从针到流体的热传递率是通过应用牛顿加热来控制的，而不是通过针对所有参数应用规定的表面温度。此外，我们进行了统计分析，以确定物理参数对两种加热过程情况下传热速率的依赖性。从针到流体的热传递率是通过应用牛顿加热来控制的，而不是通过针对所有参数应用规定的表面温度。此外，我们进行了统计分析，以确定物理参数对两种加热过程情况下传热速率的依赖性。从针到流体的热传递率是通过应用牛顿加热来控制的，而不是通过针对所有参数应用规定的表面温度。此外，我们进行了统计分析，以确定物理参数对两种加热过程情况下传热速率的依赖性。