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A School-Based SARS-CoV-2 Testing Program: Testing Uptake and Quarantine Length After In-School Exposures.
Pediatrics ( IF 8 ) Pub Date : 2022-02-01 , DOI: 10.1542/peds.2021-054268j
Angelique E Boutzoukas 1, 2 , Kanecia O Zimmerman 1, 2, 3 , Tara K Mann 2 , Ganga S Moorthy 1, 2 , Ashley Blakemore 2 , Kathleen A McGann 1 , Michael J Smith 1 , Boen Nutting 4 , Karen Kerley 4 , M Alan Brookhart 5 , Laura Edwards 2 , Zsolt Rak 2 , Daniel K Benjamin 1, 2, 3 , Ibukunoluwa C Kalu 1
Affiliation  

OBJECTIVES Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related quarantines, which are required after close contact with infected individuals, have substantially disrupted in-person education for kindergarten through 12th grade (K-12) students. In recent recommendations, shortened durations of quarantine are allowed if a negative SARS-CoV-2 test result is obtained at 5 to 7 days postexposure, but access to testing remains limited. We hypothesized that providing access to in-school SARS-CoV-2 testing postexposure would increase testing and reduce missed school days. METHODS This prospective cohort study was conducted in one large public K-12 school district in North Carolina and included 2 periods: preimplementation (March 15, 2021, to April 21, 2021) and postimplementation (April 22, 2021, to June 4, 2021), defined around initiation of an in-school SARS-CoV-2 testing program in which on-site access to testing is provided. Number of quarantined students and staff, testing uptake, test results, and number of missed school days were analyzed and compared between the preimplementation and postimplementation periods. RESULTS Twenty-four schools, including 12 251 in-person learners, participated in the study. During preimplementation, 446 close contacts were quarantined for school-related exposures; 708 close contacts were quarantined postimplementation. Testing uptake after school-related exposures increased from 6% to 40% (95% confidence interval: 23% to 45%) after implementation, and 89% of tests were conducted in-school. After in-school testing implementation, close contacts missed ∼1.5 fewer days of school (95% confidence interval: -2 to -1). CONCLUSIONS Providing access to in-school testing may be a worthwhile mechanism to increase testing uptake after in-school exposures and minimize missed days of in-person learning, thereby mitigating the pandemic's ongoing impact on children.

中文翻译:

以学校为基础的 SARS-CoV-2 检测计划:测试校内暴露后的吸收情况和隔离时长。

目标 与感染者密切接触后需要进行与严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 相关的隔离,这严重扰乱了幼儿园至 12 年级 (K-12) 学生的面对面教育。在最近的建议中,如果在暴露后 5 至 7 天获得阴性 SARS-CoV-2 检测结果,则允许缩短隔离时间,但获得检测的机会仍然有限。我们假设,提供暴露后在学校进行 SARS-CoV-2 检测的机会将增加检测次数并减少缺课天数。方法 这项前瞻性队列研究在北卡罗来纳州的一个大型公立 K-12 学区进行,包括 2 个阶段:实施前(2021 年 3 月 15 日至 2021 年 4 月 21 日)和实施后(2021 年 4 月 22 日至 2021 年 6 月 4 日) ),围绕启动校内 SARS-CoV-2 检测计划而定义,其中提供现场检测。对实施前和实施后期间被隔离的学生和教职员工人数、检测情况、检测结果以及旷课天数进行了分析和比较。结果 24 所学校(包括 12 251 名现场学习者)参与了这项研究。实施前,446名密切接触者因学校相关暴露而被隔离;实施后,708名密切接触者已被隔离。实施后,学校相关暴露后的测试采用率从 6% 增加至 40%(95% 置信区间:23% 至 45%),并且 89% 的测试在学校内进行。实施校内测试后,密切接触者缺课天数减少约 1.5 天(95% 置信区间:-2 至 -1)。结论 提供校内测试可能是一种有价值的机制,可以提高校内测试后的测试率,并最大限度地减少错过面对面学习的天数,从而减轻大流行对儿童的持续影响。
更新日期:2021-11-04
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