Background The left ventricular outflow tract (LVOT) and ascending aorta are spatially complex, with distinct pathologies and embryologic origins. Prior work examined genetics of thoracic aortic diameter in a single plane. We sought to elucidate the genetic basis for the diameter of the LVOT, the aortic root, and the ascending aorta.

中文翻译：

---

使用机器学习阐明升主动脉的空间和遗传复杂性

背景左心室流出道 (LVOT) 和升主动脉空间复杂，具有不同的病理学和胚胎学起源。先前的工作检查了单个平面中胸主动脉直径的遗传学。我们试图阐明 LVOT、主动脉根部和升主动脉直径的遗传基础。