Following identification of limbal stem cells, efforts have been devoted to restore and/or replace these essential progenitors of the corneal epithelium. Limbal stem cell deficiency, commonly a consequence of ocular chemical injury, results in clinically compromised vision consequent to corneal conjunctivalization. The insight of Kim and Tseng provided experimental proof of the concept that even in the presence of total limbal stem cell deficiency, amnion membrane overlay grafts can promote limbal recovery as a means of ocular surface reconstruction.

中文翻译：

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角膜经典文章评论：Kim JC 和 Tseng SCG：保存羊膜移植用于严重受损兔角膜表面重建（Cornea 14：473-484；1995）。

在鉴定出角膜缘干细胞后，人们致力于恢复和/或替换这些角膜上皮的重要祖细胞。角膜缘干细胞缺乏通常是眼部化学损伤的结果，导致角膜结膜化导致临床视力受损。Kim 和 Tseng 的见解提供了实验证明，即使在角膜缘干细胞完全缺乏的情况下，羊膜覆盖移植物也可以作为眼表重建的一种手段促进角膜缘恢复。