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Color Cherenkov imaging of clinical radiation therapy
Light: Science & Applications ( IF 19.4 ) Pub Date : 2021-11-04 , DOI: 10.1038/s41377-021-00660-0
Daniel A Alexander 1, 2 , Anthony Nomezine 1 , Lesley A Jarvis 3, 4 , David J Gladstone 1, 3, 4 , Brian W Pogue 1, 2, 3, 4 , Petr Bruza 1, 2
Affiliation  

Color vision is used throughout medicine to interpret the health and status of tissue. Ionizing radiation used in radiation therapy produces broadband white light inside tissue through the Cherenkov effect, and this light is attenuated by tissue features as it leaves the body. In this study, a novel time-gated three-channel camera was developed for the first time and was used to image color Cherenkov emission coming from patients during treatment. The spectral content was interpreted by comparison with imaging calibrated tissue phantoms. Color shades of Cherenkov emission in radiotherapy can be used to interpret tissue blood volume, oxygen saturation and major vessels within the body.



中文翻译:

临床放射治疗的彩色切伦科夫成像

整个医学都使用色觉来解释组织的健康和状态。放射治疗中使用的电离辐射通过切伦科夫效应在组织内产生宽带白光,这种光在离开身体时会被组织特征衰减。在这项研究中,首次开发了一种新型的时间门控三通道相机,用于对治疗期间来自患者的彩色切伦科夫发射成像。通过与成像校准的组织体模进行比较来解释光谱内容。放射治疗中切伦科夫发射的颜色深浅可用于解释组织血容量、氧饱和度和体内主要血管。

更新日期:2021-11-04
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