In this issue of Cancer Cell, Xue et al. demonstrate that adoptive transfer of tumor-specific Th9 cells can eradicate established tumors containing antigen-loss-variant cells (ALVs) through both direct killing and bystander effects mediated by intratumoral accumulation of extracellular ATP (eATP) that promotes monocyte infiltration and stimulation of IFNα/β production.

中文翻译：

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肿瘤特异性 Th9 细胞的过继转移根除表达异质抗原的肿瘤细胞

在本期Cancer Cell 中，Xue 等人。证明肿瘤特异性 Th9 细胞的过继转移可以通过直接杀伤和由细胞外 ATP (eATP) 的肿瘤内积累介导的旁观者效应根除含有抗原丢失变异细胞 (ALV) 的肿瘤，促进单核细胞浸润和刺激 IFNα/ β 生产。