Abstract

Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection fraction (EF) and the condition is termed heart failure with preserved ejection fraction (HFpEF). It is assumed that in these patients HF is due primarily to LV diastolic dysfunction. The prognosis in HFpEF is almost as severe as in HF with reduced EF (HFrEF). In contrast to HFrEF where drugs and devices are proven to reduce mortality, in HFpEF there has been limited therapy available with documented effects on prognosis. This may reflect that HFpEF encompasses a wide range of different pathological processes, which multimodality imaging is well placed to differentiate. Progress in developing therapies for HFpEF has been hampered by a lack of uniform diagnostic criteria. The present expert consensus document from the European Association of Cardiovascular Imaging (EACVI) provides recommendations regarding how to determine elevated LV filling pressure in the setting of suspected HFpEF and how to use multimodality imaging to determine specific aetiologies in patients with HFpEF.

中文翻译：

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射血分数保留的心力衰竭患者的多模态成像：欧洲心血管成像协会的专家共识文件

摘要

将近一半的心力衰竭 (HF) 患者左心室 (LV) 射血分数 (EF) 正常，这种情况被称为射血分数正常的心力衰竭 (HFpEF)。据推测，在这些患者中，HF 主要是由于 LV 舒张功能障碍。HFpEF 的预后几乎与 EF 降低的 HF (HFrEF) 一样严重。与药物和设备被证明可降低死亡率的 HFrEF 相比，在 HFpEF 中，可用的治疗方法有限，且已证明对预后有影响。这可能反映出 HFpEF 包含范围广泛的不同病理过程，多模态成像非常适合区分这些过程。缺乏统一的诊断标准阻碍了开发 HFpEF 疗法的进展。