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Scientific Evidence Supporting Coronavirus Disease 2019 (COVID-19) Vaccine Efficacy and Safety in People Planning to Conceive or Who Are Pregnant or Lactating.
Obstetrics and Gynecology ( IF 5.7 ) Pub Date : 2021-11-02 , DOI: 10.1097/aog.0000000000004636
Guillermina Girardi 1 , Andrew A Bremer
Affiliation  

Three coronavirus disease 2019 (COVID-19) vaccines have been authorized for use in the United States; specifically, the Pfizer-BioNTech, Moderna, and Johnson & Johnson-Janssen COVID-19 vaccines were granted emergency use authorization by the U.S. Food and Drug Administration in late 2020 and early 2021. Vaccination coverage and intent among adults are lowest among those aged 18-39 years and among females in particular. In females of reproductive age, enthusiasm for receiving a COVID-19 vaccine may be negatively affected by claims currently circulating widely on diverse social media platforms regarding the vaccines adversely affecting fertility and pregnancy. Yet it is important to note that these claims are anecdotal in nature and not supported by the available scientific evidence. It is also imperative that the effects of COVID-19 vaccine on reproductive health are clarified. Herein, we discuss the existing scientific data supporting COVID-19 vaccine safety and efficacy in people who are planning to conceive or who are pregnant or lactating and highlight the importance of COVID-19 vaccination in females of reproductive age.

中文翻译:

支持 2019 年冠状病毒病 (COVID-19) 疫苗对计划怀孕或怀孕或哺乳期人群的功效和安全性的科学证据。

三种 2019 年冠状病毒病 (COVID-19) 疫苗已获授权在美国使用;具体而言,辉瑞-BioNTech、Moderna和强生-杨森的COVID-19疫苗于2020年底和2021年初获得美国食品和药物管理局的紧急使用授权。18岁人群中成年人的疫苗接种覆盖率和意愿最低-39岁,尤其是女性。在育龄女性中,目前在各种社交媒体平台上广泛流传的有关疫苗对生育和怀孕产生不利影响的说法可能会对育龄女性接种 COVID-19 疫苗的热情产生负面影响。但值得注意的是,这些说法本质上是轶事,并没有得到现有科学证据的支持。澄清 COVID-19 疫苗对生殖健康的影响也势在必行。在此,我们讨论支持计划怀孕或怀孕或哺乳期人群中的 COVID-19 疫苗安全性和有效性的现有科学数据,并强调育龄女性接种 COVID-19 疫苗的重要性。
更新日期:2021-11-02
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