Purpose: 

The purpose of this study was to describe a case of conjunctival melanoacanthoma, an exceedingly rare condition that has yet to be fully described in the literature.

Methods: 

Melanoacanthomas are most commonly seen on the skin or oral mucosa and are believed to result from local irritation or trauma. A 34-year-old Hispanic man presented with a painless, solitary, pigmented conjunctival lesion, in addition to bilateral pterygia suggesting chronic solar damage. The lesion was excised and sent for analysis.

Results: 

Histopathologic analysis of tissue samples demonstrated melanocyte proliferation and epithelial dysplasia, yielding a final pathologic diagnosis of conjunctival melanoacanthoma with dysplastic and acantholytic-type features. The patient is being closely followed and has not had recurrence of the lesion.

Conclusions: 

Only 1 prior case of conjunctival melanoacanthoma has been documented. As such, there is no standard of care regarding appropriate management.

中文翻译：

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结膜黑色素棘皮瘤一例报告

目的： 

这项研究的目的是描述一例结膜黑色素棘皮瘤病例，这是一种极其罕见的疾病，尚未在文献中得到充分描述。

方法： 

黑色素棘皮瘤最常见于皮肤或口腔粘膜，被认为是由局部刺激或创伤引起的。一名 34 岁的西班牙裔男性出现无痛性、孤立性、色素性结膜病变，此外还有双侧翼状胬肉，提示有慢性日光损伤。病变被切除并送去分析。

结果： 

组织样本的组织病理学分析显示黑色素细胞增殖和上皮发育不良，最终病理诊断为具有发育不良和棘层松解型特征的结膜黑色素棘皮瘤。该患者正在接受密切随访，病变尚未复发。

结论： 

先前仅记录 1 例结膜黑色素棘皮瘤病例。因此，没有关于适当管理的护理标准。