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Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2–Associated Deaths
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2021-11-02 , DOI: 10.3201/eid2801.211749
Fabian Heinrich , Ann Sophie Schröder , Anna-Lina Gerberding , Moritz Gerling , Felicia Langenwalder , Philine Lange , Axel Heinemann , Eric Bibiza-Freiwald , Dominik Sebastian Nörz , Martin Aepfelbacher , Susanne Pfefferle , Benjamin Ondruschka , Marc Lütgehetmann

We investigated the infectivity of 128 severe acute respiratory disease coronavirus 2–associated deaths and evaluated predictive values of standard diagnostic procedures. Maintained infectivity (20%) did not correlate with viral RNA loads but correlated well with anti-S antibody levels. Sensitivity >90% for antigen-detecting rapid diagnostic tests supports their usefulness for assessment.



中文翻译:

死后抗原检测快速诊断测试可预测 SARS-CoV-2 相关死亡的传染性

我们调查了 128 例严重急性呼吸道疾病冠状病毒 2 相关死亡的传染性,并评估了标准诊断程序的预测价值。保持感染性 (20%) 与病毒 RNA 载量无关,但与抗 S 抗体水平相关。抗原检测快速诊断测试的灵敏度 >90% 支持其评估的有用性。

更新日期:2021-11-03
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