Purpose

To evaluate and compare the effects of different intraocular tamponade agents on lens density after vitrectomy.

Methods

The participating patients were divided into four groups according to the tamponade agent used: a sulfur hexafluoride (SF₆) group, a perfluoropropane (C₃F₈) group, a silicone oil group, and a no tamponade group. Lens density measurements were performed preoperatively and two weeks, one month, and three months postoperatively using a Pentacam HR device with a Scheimpflug camera. The postoperative values were compared with the preoperative baseline values, also the values were compared between the four groups.

Results

The study included 82 eyes (82 patients). In the SF₆ group, lens density significantly increased in all zones two weeks and one and three months postoperatively (all P < .05). In the C₃F₈ group, lens density significantly increased in all zones three months postoperatively (all P < .01). In the silicone oil group, the zone 1, zone 2, and average lens density (ALD) value significantly increased one and three months postoperatively (all P < .05). In the no tamponade group, the zone 1, zone 2, and ALD values significantly increased three months postoperatively (all P < .05). There were no significant differences between the four groups in any zone either preoperatively or postoperatively (all P > .05).

Conclusions

Although increases in lens density were observed earlier in the tamponade groups than in the no tamponade group, between the groups over the follow-up period were no differences. We need the development of new surgical methods and materials to prevent post-vitrectomy lens damage in the future.

中文翻译：

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不同玻璃体内填塞物玻璃体切除术后晶状体透明度的客观评价

目的

评估和比较不同眼内填塞剂对玻璃体切除术后晶状体密度的影响。

方法

参与的患者根据所使用的填塞剂分为四组：六氟化硫（SF ₆）组、全氟丙烷（C ₃ F ₈）组、硅油组和无填塞剂组。使用带有 Scheimpflug 相机的 Pentacam HR 设备在术前和术后 2 周、1 个月和 3 个月进行晶状体密度测量。将术后值与术前基线值进行比较，并对四组之间的值进行比较。

结果

该研究包括 82 只眼睛（82 名患者）。在 SF ₆组，术后 2 周、1 个月和 3 个月，所有区域的晶状体密度均显着增加（均P  < .05）。在 C ₃ F ₈组中，术后三个月所有区域的晶状体密度均显着增加（均P  < .01）。在硅油组，术后 1 个月和 3 个月，1 区、2 区和平均晶状体密度（ALD）值显着增加（均P  < .05）。在无填塞组中，1 区、2 区和 ALD 值在术后 3 个月显着增加（所有P < .05)。四组在术前或术后任何区域均无显着差异（均P  > .05）。

结论

尽管在填塞组中观察到晶状体密度的增加比在无填塞组中更早，但在随访期间各组之间没有差异。我们需要开发新的手术方法和材料，以防止未来玻璃体切除术后晶状体损伤。