Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332,Protein & Cell

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Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332
Protein & Cell ( IF 21.1 ) Pub Date : 2021-10-22 , DOI: 10.1007/s13238-021-00883-2
Yao Zhao ₁ , Chao Fang ₂ , Qi Zhang _{1,

3,

4} , Ruxue Zhang ₅ , Xiangbo Zhao ₂ , Yinkai Duan ₁ , Haofeng Wang ₁ , Yan Zhu ₁ , Lu Feng ₁ , Jinyi Zhao ₁ , Maolin Shao ₁ , Xiuna Yang ₁ , Leike Zhang ₅ , Chao Peng ₆ , Kailin Yang ₇ , Dawei Ma ₂ , Zihe Rao _{1,

8,

9} , Haitao Yang ₁

Affiliation

Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
State Key Laboratory of Bioorganic & Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.
CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, 200031, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210, China.
Taussig Cancer Center, Cleveland Clinic, Cleveland, OH, 44195, USA.
Laboratory of Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing, 100091, China.
State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Response, College of Life Sciences, Nankai University, and Tianjin Key Laboratory of Protein Sciences, Tianjin, 300071, China.