OBJECTIVES The goal of this study was to assess the performance and incidence of the deterioration of the Labcor Dokimos bioprosthetic aortic valve. METHODS We performed a retrospective medical chart review of 116 patients who underwent surgical aortic valve replacement with the Labcor Dokimos aortic valve between 2010 and 2018. ed data included patient demographic and echocardiographic data. Patients were divided into 2 groups: patients with structural valve deterioration (SVD) and patients without SVD. RESULTS Among the patients with complete follow-up (n = 95), 10 patients were excluded because they died within a year; 85 patients were included in the final analysis. Of the 85 patients, 32 (38%) developed SVD; 22 (26%) had severe SVD, 15 (18%) of whom underwent reintervention. The most common aetiology of SVD was severe central aortic regurgitation, which was detected in 91% of the patients who had severe SVD. The average time from operation to severe SVD was 4.7 years with a minimum of 1.5 years and a maximum of 7.9 years. CONCLUSIONS Bioprosthetic aortic valve deterioration due to severe aortic regurgitation is common and occurs early with the Labcor Dokimos valve. This occurrence needs to be furthered investigated in larger registries.

中文翻译：

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Labcor Dokimos 主动脉假体的结构性瓣膜恶化：单中心经验


目的 本研究的目的是评估 Labcor Dokimos 生物主动脉瓣的性能和恶化发生率。方法 我们对 2010 年至 2018 年间接受 Labcor Dokimos 主动脉瓣主动脉瓣置换术的 116 名患者进行了回顾性病历审查。编辑数据包括患者人口统计和超声心动图数据。患者被分为两组：有结构性瓣膜恶化（SVD）的患者和无 SVD 的患者。结果 完成随访的患者（n=95）中，有10例因一年内死亡而被排除；最终分析纳入85例患者。在 85 名患者中，32 名（38%）患有 SVD； 22 人 (26%) 患有严重 SVD，其中 15 人 (18%) 接受了再干预。 SVD 最常见的病因是严重的中央主动脉瓣关闭不全，91% 的严重 SVD 患者均检测到这种情况。从手术到严重SVD的平均时间为4.7年，最短1.5年，最长7.9年。结论 由于严重主动脉瓣关闭不全导致的生物主动脉瓣退化很常见，并且在使用 Labcor Dokimos 瓣膜时较早发生。这种情况需要在更大的登记处进一步调查。