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Expression of chimeric antigen receptor therapy targets detected by single-cell sequencing of normal cells may contribute to off-tumor toxicity.
Cancer Cell ( IF 48.8 ) Pub Date : 2021-10-21 , DOI: 10.1016/j.ccell.2021.09.016
Ying Jing 1 , Yuan Liu 2 , Qiang Li 2 , Youqiong Ye 3 , Lixia Diao 4 , Yun Huang 5 , Yubin Zhou 6 , Michael R Green 7 , Gordon B Mills 8 , Leng Han 9
Affiliation  



中文翻译:

通过正常细胞的单细胞测序检测到的嵌合抗原受体治疗靶点的表达可能导致肿瘤外毒性。

更新日期:2021-10-19
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