Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.,Critical Care Medicine

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Tranexamic Acid in Gastrointestinal Bleeding: A Systematic Review and Meta-Analysis.
Critical Care Medicine ( IF 7.7 ) Pub Date : 2021-10-27 , DOI: 10.1097/ccm.0000000000005362
Joanna C Dionne _{1,

2,

3} , Simon J W Oczkowski _{1,

2,

3} , Beverley J Hunt _{4,

5} , Massimo Antonelli _{6,

7} , Marije Wijnberge _{8,

9} , Senta Jorinde Raasveld ₉ , Alexander P J Vlaar ₉ ,

Affiliation

Tranexamic acid is proposed as a treatment for gastrointestinal bleeding. The Haemorrhage Alleviation with Tranexamic Acid-Intestinal System trial evaluated extended-use (24 hr) high-dose tranexamic acid, prompting a reappraisal for tranexamic acid in gastrointestinal bleeding.

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