Evaluate outcomes of single leaflet aortic valve reconstruction using Ozaki sizer and template. Single institute retrospective analysis between August 2015 and August 2019. Thirty-three patients, median age 9.3 years and weight 29.2 kg underwent single leaflet Ozaki repair. Preoperative indications were: AR (n = 17), AS (n = 3) or AS/AR (n = 13). Baseline anatomy was unicuspid (n = 15), bicuspid (n = 9) or tricuspid (n = 9). Two patients had endocarditis. Prior interventions included balloon valvuloplasty (n = 22) and aortic valve repair (n = 9). Pre-op average native annulus diameter was 19.6 mm and peak echo gradient was 36 mm Hg. Autologous pericardium, Photofix and CardioCel bovine pericardium were used in 26, 5, and 2 patients. Non-coronary sinus enlargement was required in 3 and aortic root reduction in 9 patients. Single leaflet reconstruction was done for the right coronary cusp (n = 25), non-coronary cusp in (n = 6) and left coronary cusp (n = 2). Additional procedures were done in 30 patients. Median ICU and hospital LOS were 2.1 and 6.3 days. There were no early re-interventions or conversions to valve replacement and one unrelated mortality.en At discharge, all patients had < moderate AR and/or AS with average peak gradients of 15 mm Hg. The median follow-up was 1.1 year, (IQR 0.7–1.8 years). Freedom from ≥ moderate AR and AS at 2 years was 76% and 86%. One patient required surgical re-intervention for severe AR 1.5 years after surgery for inflammatory infiltrate with calcification and fibrosis. Single-leaflet aortic valve leaflet reconstruction utilizing the Ozaki technique has promising early results and can be considered in patients when there are acceptable native leaflets.

使用 Ozaki sizer 和模板评估单叶主动脉瓣重建的结果。2015年8月至2019年8月单机构回顾性分析。33例患者，中位年龄9.3岁，体重29.2 kg，行单叶Ozaki修复。术前适应症为： AR (n = 17)、AS (n = 3) 或 AS/AR (n = 13)。基线解剖结构为单尖瓣 (n = 15)、二尖瓣 (n = 9) 或三尖瓣 (n = 9)。两名患者患有心内膜炎。先前的干预措施包括球囊瓣膜成形术(n = 22) 和主动脉瓣修复 (n = 9)。术前平均原生瓣环直径为 19.6 毫米，峰值回波梯度为 36 毫米汞柱。自体心包膜、Photofix 和 CardioCel 牛心包膜分别用于 26 例、5 例和 2 例患者。3 例需要非冠状窦扩大，9 例需要主动脉根部缩小。对右冠状动脉尖 (n = 25)、非冠状动脉尖 (n = 6) 和左冠状动脉尖 (n = 2) 进行单叶重建。对 30 名患者进行了额外的手术。ICU 和医院 LOS 的中位数分别为 2.1 天和 6.3 天。没有早期再干预或转为瓣膜置换术，也没有发生一例无关的死亡。en 出院时，所有患者均有 < 中度 AR 和/或 AS，平均峰值压差为 15 mm Hg。中位随访时间为 1.1 年（IQR 0.7-1.8 年）。2 年时无≥中度 AR 和 AS 的比例分别为 76% 和 86%。一名患者在手术后 1.5 年因严重 AR 需要再次手术干预炎症浸润伴随钙化和纤维化。利用 Ozaki 技术的单叶主动脉瓣叶重建具有可喜的早期结果，并且当有可接受的原生小叶时可以考虑用于患者。