Neuhöfer et al. have identified a rare subpopulation of pancreatic acinar cells in the exocrine compartment that renews the pancreas by fuelling clonal expansion. When harbouring Kras mutations, these acinar cells accelerated clone formation and might represent an early cancer precursor lesion.

中文翻译：

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将胰腺更新与癌症发生联系起来

Neuhöfer 等人。已经在外分泌室中发现了一种罕见的胰腺腺泡细胞亚群，它通过促进克隆扩张来更新胰腺。当携带 Kras 突变时，这些腺泡细胞会加速克隆形成，并可能代表早期癌症前体病变。