The comorbidity between physical and mental health conditions is challenging and frequently goes unrecognized in practice. Associations between Attention-Deficit/Hyperactivity Disorder (ADHD) and physical conditions have been reported in youth. However, prior research failed to: (1) address the patterns of associations in early childhood, middle childhood, and adolescence within the same population sample; (2) consider a large set of physical disorders at the same time; (3) take confounders into account. Our goal was to assess the associations between ADHD symptoms and a broad set of physical conditions across developmental periods. This birth cohort study (n = 2057) is the first to explore the associations between ADHD and a wide range of medical conditions by encompassing the whole early development from 5 months to 17 years in the same sample and relying on innovative network analyses. We found significant associations between ADHD symptoms and several physical conditions, some of which were observed in early childhood, middle childhood, and adolescence (e.g., asthma, sleep problems) or were confounded by socioeconomic status or psychiatric comorbidities (e.g., body mass index, dental caries). The study calls for an effective integrated care model encompassing mental and general healthcare across the developmental period.

身体和精神健康状况之间的合并症具有挑战性，并且在实践中经常得不到承认。注意力缺陷/多动障碍 (ADHD) 与身体状况之间的关联已在青少年中得到报道。然而，之前的研究未能：(1) 解决同一人群样本中儿童早期、儿童中期和青春期的关联模式；(2) 同时考虑一大组躯体障碍；(3) 考虑混杂因素。我们的目标是评估 ADHD 症状与整个发育时期的广泛身体状况之间的关联。这项出生队列研究（n = 2057) 是第一个通过在同一样本中涵盖从 5 个月到 17 岁的整个早期发展并依靠创新网络分析来探索 ADHD 与广泛医学状况之间关联的人。我们发现 ADHD 症状与几种身体状况之间存在显着关联，其中一些在儿童早期、儿童中期和青春期（例如，哮喘、睡眠问题）观察到，或者被社会经济状况或精神疾病（例如，体重指数、龋齿）。该研究呼吁建立一个有效的综合护理模式，涵盖整个发育时期的心理和一般保健。