As the prognosis for multiple myeloma (MM) has significantly improved and patients remain on therapy longer, there is a need for supportive care interventions to optimize patient quality of life (QOL) and functional status over the course of cancer treatment. MM is characterized by a significant symptom burden and a relatively lower QOL compared to other cancers. This review evaluates the role of healthy lifestyle behaviors in improving both the physical functioning and psychological well-being of the MM population. We (1) describe the current literature on physical activity, weight management, diet, sleep, and substance use in the context of MM, (2) present important considerations for incorporating lifestyle factors into clinical practice, and (3) identify directions for future research. Developing MM-specific guidelines for modifiable lifestyle changes that take into account both the length of treatment and the unique disease features (i.e. osteolytic lesions and anemia) may provide a promising path for improved patient QOL and functioning.

由于多发性骨髓瘤 (MM) 的预后已显着改善且患者接受治疗的时间更长，因此需要支持性护理干预以优化患者在癌症治疗过程中的生活质量 (QOL) 和功能状态。与其他癌症相比，MM 的特征是显着的症状负担和相对较低的 QOL。本综述评估了健康生活方式行为在改善 MM 人群身体机能和心理健康方面的作用。我们 (1) 在 MM 的背景下描述当前关于身体活动、体重管理、饮食、睡眠和物质使用的文献，(2) 提出将生活方式因素纳入临床实践的重要考虑因素，以及 (3) 确定未来的方向研究。