In this issue of Developmental Cell, Campbell et al. (2021) show that melanoma cells with distinct invasive or proliferative gene signatures can form heterotypic clusters that extravasate collectively and readily seed the growth of metastatic lesions. These findings highlight interactions between heterogenous tumor cells as being critical for metastasis.

中文翻译：

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协同工作：黑色素瘤转移中的异型簇和集体细胞迁移

在本期Developmental Cell 中，Campbell 等人。(2021) 表明，具有不同侵袭性或增殖性基因特征的黑色素瘤细胞可以形成异型簇，这些簇一起外渗并容易为转移性病变的生长提供种子。这些发现强调异质肿瘤细胞之间的相互作用对转移至关重要。