Rotta et al.¹ performed a 7T MRI study and found that approximately 14% of microbleeds (MBs) were related to a venous source using a Quantitative Susceptibility Mapping (QSM) sequence, challenging the artery origin of MBs.² We support the notion that a certain number of MBs are closely connected to veins, which can also be visualized with 3T MRI Susceptibility Weighted Imaging (SWI) or QSM techniques. Indeed, the microbleed connection with veins may be more prevalent in the cortex.¹ However, one should be aware that MBs in the cortex are more difficult to differentiate from the vessels than those deep and infratentorial MBs, especially in individuals with mild MBs burden.^3,4 In this study,¹ the control group had a low microbleed burden, whereas 25 of 31 healthy controls had at least 1 MB present (81%), which was higher than the prevalence reported from community studies (15%). It is possible that some vascular structures were misjudged as MBs in some patients.

罗塔等人。¹进行了一项 7T MRI 研究，发现大约 14% 的微出血 (MB) 与使用定量磁敏度映射 (QSM) 序列的静脉源有关，这对 MB 的动脉起源提出了挑战。²我们支持一定数量的 MB 与静脉紧密相连的观点，这也可以通过 3T MRI 磁敏感加权成像 (SWI) 或 QSM 技术进行可视化。事实上，与静脉的微出血连接可能在皮质中更为普遍。¹然而，人们应该意识到皮质中的 MBs 比那些深部和幕下 MBs 更难与血管区分开来，尤其是在具有轻度 MBs 负担的个体中。^3,4在本研究中，¹对照组的微出血负担较低，而 31 名健康对照组中有 25 名至少存在 1 MB (81%)，高于社区研究报告的流行率 (15%)。在某些患者中，某些血管结构可能被误判为 MB。