Purpose: 

The purpose of this study was to evaluate the features of and relationships among corneal diameter, central corneal thickness (CCT), endothelial cell density (ECD), and corneal refractive properties in cases of microcornea (MC) with normal axial length.

Methods: 

We included 22 patients (35 eyes) with MC and cataracts and 41 patients (48 eyes) with isolated cataracts as age-matched controls. They were divided into patients with MC younger than 18 years (MC-child), patients with MC 18 years or older (MC-adult), children with congenital cataracts (CCs), and adults with senile cataracts (SCs). Corneal diameter, axial and anterior chamber length, and keratometry were measured; central corneal endothelial cell imaging was performed.

Results: 

The mean horizontal corneal diameter was 7.71 ± 1.51 and 8.78 ± 0.52 mm in MC-child and MC-adult groups, respectively, and 11.89 ± 0.59 and 11.52 ± 2.42 mm in child and adult controls, respectively. The mean CCT was 641.26 ± 63.37 (MC-child) and 617.38 ± 45.40 mm (MC-adult), and 554.92 ± 34.64 (CC) and 551.58 ± 28.47 mm (SC). The mean ECD was 2898.47 ± 443.90 (MC-child) and 2825.81 ± 484.65 cells/mm² (MC-adult), and 3155.13 ± 372.67 (CC) and 2749.33 ± 399.63 cells/mm² (SC). The average keratometry was 44.22 ± 3.14 D (MC-child) and 43.86 ± 2.59 D (MC-adult), and 44.19 ± 1.44 D (CC) and 43.94 ± 1.34 D (SC).

Conclusions: 

Patients with MC and normal axial length possess specific parameters, including significantly smaller corneal diameter and thicker CCT than the patients in the control groups. There were no significant differences in ECD and average keratometry. These parameters should be taken into account in the follow-up and treatment.

中文翻译：

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正常眼轴微角膜的角膜生物参数和屈光特性

目的： 

本研究的目的是评估眼轴正常的微角膜（MC）病例中角膜直径、中央角膜厚度（CCT）、内皮细胞密度（ECD）和角膜屈光特性的特征及其之间的关系。

方法： 

我们纳入了 22 名患有 MC 和白内障的患者（35 只眼）和 41 名患有孤立性白内障的患者（48 只眼）作为年龄匹配的对照。他们被分为18岁以下的MC患者（MC-儿童）、18岁或以上的MC患者（MC-成人）、儿童先天性白内障（CC​​）和成人老年性白内障（SC）。测量角膜直径、眼轴和前房长度以及角膜曲率；进行中央角膜内皮细胞成像。

结果： 

MC 儿童组和 MC 成人组的平均水平角膜直径分别为 7.71 ± 1.51 和 8.78 ± 0.52 mm，儿童和成人对照组分别为 11.89 ± 0.59 和 11.52 ± 2.42 mm。平均 CCT 为 641.26 ± 63.37（MC 儿童）和 617.38 ± 45.40 mm（MC 成人），以及 554.92 ± 34.64（CC）和 551.58 ± 28.47 mm（SC）。平均ECD为2898.47±443.90（MC-儿童）和2825.81±484.65细胞/mm ²（MC-成人），以及3155.13±372.67（CC）和2749.33±399.63细胞/mm ²（SC）。平均角膜曲率为 44.22 ± 3.14 D（MC-儿童）和 43.86 ± 2.59 D（MC-成人），以及 44.19 ± 1.44 D（CC）和 43.94 ± 1.34 D（SC）。

结论： 

MC且眼轴正常的患者具有特定的参数，包括比对照组患者显着更小的角膜直径和更厚的CCT。ECD 和平均角膜曲率没有显着差异。在随访和治疗中应考虑这些参数。