Findings in 1123 Men with Pre-operative 68Ga-PSMA PET/CT and mpMRI Compared to Totally Embedded Radical Prostatectomy Histopathology. Implications for the Diagnosis and Management of Prostate Cancer.,The Journal of Urology

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Findings in 1123 Men with Pre-operative 68Ga-PSMA PET/CT and mpMRI Compared to Totally Embedded Radical Prostatectomy Histopathology. Implications for the Diagnosis and Management of Prostate Cancer.
The Journal of Urology ( IF 5.9 ) Pub Date : 2021-10-25 , DOI: 10.1097/ju.0000000000002293
S Raveenthiran _{1,

2} , W J Yaxley _{2,

3} , T Franklin ₄ , G Coughlin ₄ , M Roberts _{1,

2,

5,

6} , T Gianduzzo _{2,

7} , B Kua ₄ , H Samaratunga _{2,

8} , B Delahunt ₉ , L Egevad ₁₀ , D Wong _{5,

11} , L McEwan ₁₁ , N Brown ₁₁ , R Parkinson ₁₁ , R Esler _{2,

4,

5} , J W Yaxley _{2,

4,

5}

Affiliation

Multiparametric MRI (mpMRI) fails to identify some men with significant prostate cancer. PSMA PET/CT is recommended for staging of prostate cancer, but its additional benefit above mpMRI alone in local evaluation for prostate cancer is unclear. The study aim was to evaluate the ability of mpMRI and PSMA PET/CT individually and in combination, to predict tumour location and Gleason score ≥3+4 on robot assisted laparoscopic radical prostatectomy (RALP) histology.

中文翻译：

1123 名男性术前 68Ga-PSMA PET/CT 和 mpMRI 与完全嵌入根治性前列腺切除术组织病理学比较的结果。对前列腺癌诊断和治疗的意义。

多参数 MRI (mpMRI) 未能识别出一些患有严重前列腺癌的男性。PSMA PET/CT 被推荐用于前列腺癌的分期，但其在前列腺癌局部评估中优于单独 mpMRI 的额外益处尚不清楚。研究目的是评估 mpMRI 和 PSMA PET/CT 单独和组合在机器人辅助腹腔镜根治性前列腺切除术 (RALP) 组织学中预测肿瘤位置和 Gleason 评分≥3+4 的能力。

更新日期：2021-10-25

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