当前位置: X-MOL 学术Pediatr. Cardiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
SARS-CoV-2 in a Neonate with Truncus Arteriosus: Management and Surgical Correction Timing
Pediatric Cardiology ( IF 1.5 ) Pub Date : 2021-10-21 , DOI: 10.1007/s00246-021-02757-0
M Masci 1 , P Moras 2 , L Di Chiara 3 , L Pasquini 1 , C M Campanale 1 , P Bagolan 4 , L Galletti 5 , A Toscano 1
Affiliation  

Children seem to be less affected by SARS-CoV-2 infection. High risk categories should include patients with Congenital Heart Disease (CHD), both children and adults. We describe the case of a newborn with a postnatal diagnosis of Truncus Arteriosus (TA) type A1 without 22.q.11 deletion syndrome. Soon after birth, SARS-CoV-2 infection was transmitted by the father. Due to the onset of heart failure symptoms, diuretic therapy has been set up. For worsening of clinical conditions, inotropic support with milrinone was added. A progressive reduction of N-terminal-pro hormone BNP over the days has been observed. Fourteen days after the negativization of the nasopharyngeal swab, the patient underwent surgical repair with Cardiopulmonary Bypass (CPB). Postoperative course was not complicated and the patient was discharged in good clinical conditions. There is very little evidence suggesting the optimal timing for surgery in SARS-CoV-2 positive patients. With a lack of specific guidelines, current strategy suggests a symptom-based or a polymerase chain reaction (PCR) test-based approach. In our case it was challenging to determine COVID-19 impact on heart failure symptoms. Our case is the first describing the surgical correction of CHD in a 40 days year old patient, performed in CPB after 14 days from SARS-CoV-2 infection negativization.



中文翻译:

患有动脉干新生儿的 SARS-CoV-2:治疗和手术矫正时机

儿童似乎受 SARS-CoV-2 感染的影响较小。高风险类别应包括儿童和成人先天性心脏病 (CHD) 患者。我们描述了一个出生后诊断为 A1 型动脉干 (TA) 没有 22.q.11 缺失综合征的新生儿病例。出生后不久,SARS-CoV-2 感染由父亲传播。由于出现心力衰竭症状,已建立利尿剂治疗。为了使临床状况恶化,添加了米力农的正性肌力支持。观察到 N-末端前激素 BNP 在几天内逐渐减少。鼻咽拭子阴性后 14 天,患者接受了体外循环 (CPB) 手术修复。术后病程不复杂,患者临床情况良好出院。很少有证据表明 SARS-CoV-2 阳性患者的最佳手术时机。由于缺乏具体的指导方针,目前的策略建议采用基于症状或聚合酶链反应 (PCR) 测试的方法。在我们的案例中,确定 COVID-19 对心力衰竭症状的影响具有挑战性。我们的案例首次描述了一名 40 天岁患者的 CHD 手术矫正,该患者在 SARS-CoV-2 感染阴性 14 天后在 CPB 中进行。

更新日期:2021-10-22
down
wechat
bug