Mitral valve replacement in infants is challenging and there are limited alternative valves available. Since the Boston group published their first report on alternative valves for mitral valve replacement in infants, there has been a growth in the literature on the topic, mostly based on the use of a stented bovine jugular vein graft (Melody® valve). The challenges of the Melody valve are firstly in its length of 28 mm unexpanded, which has the potential to cause left ventricular outflow tract obstruction, and secondly, the valve needs mechanical dilatation, which is laborious. A modified No-React® Injectable Biopulmonic™ Prosthesis (Bio Integral Surgical, Inc., Mississauga, ON, Canada) which is shorter (19 mm) and simpler in that it is self-expanding was implanted in a 14-month-old child to replace her mitral valve. The operation was successful and the short-term function of the prosthesis is good.

中文翻译：

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用于幼儿二尖瓣置换的替代瓣膜：使用 NO-REACT® INJECTABLE BIOPULMONIC™ 假体作为 14 个月大儿童的二尖瓣置换

婴儿二尖瓣置换术具有挑战性，可供选择的瓣膜有限。自从波士顿小组发表了他们关于婴儿二尖瓣置换替代瓣膜的第一份报告以来，关于该主题的文献有所增加，主要是基于支架牛颈静脉移植物（Melody® 瓣膜）的使用。Melody 瓣膜的挑战首先在于其未扩张的 28 mm 长度，这有可能导致左心室流出道梗阻，其次，瓣膜需要机械扩张，这很费力。一种改良的 No-React® Injectable Biopulmonic™ 假体（Bio Integral Surgical, Inc., Mississauga, ON, Canada）被植入一个 14 个月大的儿童体内，该假体更短（19 毫米）且更简单，因为它可以自我膨胀更换她的二尖瓣。