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Goldenrod Root Compounds Active against Crop Pathogenic Fungi
Journal of Agricultural and Food Chemistry ( IF 6.1 ) Pub Date : 2021-10-19 , DOI: 10.1021/acs.jafc.1c03676
Dániel Krüzselyi 1 , József Bakonyi 1 , Péter G Ott 1 , András Darcsi 2 , Péter Csontos 3 , Gertrud E Morlock 4 , Ágnes M Móricz 1
Affiliation  

Root extracts of three goldenrods were screened for antimicrobial compounds. 2Z,8Z- and 2E,8Z-matricaria esters from European goldenrod (Solidago virgaurea) and E- and Z-dehydromatricaria esters from grass-leaved goldenrod (Solidago graminifolia) and first from showy goldenrod (Solidago speciosa) were identified by high-performance thin-layer chromatography combined with effect-directed analysis and high-resolution mass spectrometry or nuclear magnetic resonance spectroscopy after liquid chromatographic fractionation and isolation. Next to their antibacterial effects (against Bacillus subtilis, Aliivibrio fischeri, and Pseudomonas syringae pv. maculicola), they inhibited the crop pathogenic fungi Fusarium avenaceum and Bipolaris sorokiniana with half maximal inhibitory concentrations (IC50) between 31 and 107 μg/mL. Benzyl 2-hydroxy-6-methoxybenzoate, for the first time found in showy goldenrod root, showed the strongest antifungal effect, with IC50 of 25–26 μg/mL for both fungal strains.

中文翻译:

具有抗作物病原真菌活性的黄花根化合物

筛选了三种黄花的根提取物的抗微生物化合物。鉴定了来自欧洲一枝黄花Solidago virgaurea)的2 Z ,8 Z - 和2 E ,8 Z -母菊酯以及来自草叶一枝黄花Solidago graminifolia)的E - 和Z -脱氢母菊酯以及首先来自艳丽的一枝黄花Solidago speciosa)的E - 和Z -脱氢母菊酯。通过高效薄层色谱结合效应导向分析和高分辨率质谱或核磁共振光谱,经过液相色谱分馏和分离。除了它们的抗菌作用(针对枯草芽孢杆菌)Aliivibrio fischeriPseudomonas syringae pv。maculicola ),它们抑制作物病原真菌Fusarium avenaceumBipolaris sorokiniana,半数最大抑制浓度 (IC 50 ) 介于 31 和 107 μg/mL 之间。2-羟基-6-甲氧基苯甲酸苄酯首次在艳丽的黄花根中发现,显示出最强的抗真菌作用,两种真菌菌株的IC 50为25-26 μg/mL。
更新日期:2021-11-03
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