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The role of mprF mutations in “see-saw effect” of Daptomycin-resistant methicillin-resistant Staphylococcus aureus isolates
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-10-18 , DOI: 10.1128/aac.01295-21
Shengnan Jiang 1, 2 , Hemu Zhuang 1, 2 , Feiteng Zhu 1, 2 , Xiang Wei 2, 3 , Junxiong Zhang 1, 4 , Lu Sun 1, 2 , Shujuan Ji 1, 2 , Haiping Wang 1, 2 , Dandan Wu 5 , Feng Zhao 6 , Rushuang Yan 1, 2 , Yunsong Yu 1, 2 , Yan Chen 1, 2
Affiliation  

The emergence of daptomycin-resistant (DAP-R) Staphylococcus aureus strains has become a global problem. Point mutations in mprF are the main cause of daptomycin (DAP) treatment failure. However, the impact of these specific point-mutations in methicillin-...

中文翻译:

mprF 突变在耐达托霉素耐甲氧西林金黄色葡萄球菌分离株“跷跷板效应”中的作用

耐达托霉素 (DAP-R) 金黄色葡萄球菌菌株的出现已成为一个全球性问题。mprF 中的点突变是达托霉素 (DAP) 治疗失败的主要原因。然而,这些特定点突变对甲氧西林的影响-...
更新日期:2021-10-20
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