当前位置: X-MOL 学术Kidney Int. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Ketone bodies: back to a place in the sun
Kidney International ( IF 14.8 ) Pub Date : 2021-10-20 , DOI: 10.1016/j.kint.2021.07.022
Shinji Kume 1
Affiliation  

Ketone bodies have a strong negative image in medicine because of ketoacidosis, a life-threatening complication in diabetes. However, Fang et al. report that ketone bodies exert antisenescent effects in podocytes under diabetic conditions, via activation of the nuclear factor E2-related factor 2–related antioxidative stress pathway. With recent progression of research on longevity, the beneficial effects of ketone bodies are being clarified, and a positive image of ketone bodies is gradually beginning to develop in many research fields including nephrology.



中文翻译:

酮体:回到阳光下的地方

由于酮症酸中毒(一种危及生命的糖尿病并发症),酮体在医学上具有强烈的负面形象。然而,Fang等人。报道称,酮体在糖尿病条件下通过激活核因子 E2 相关因子 2 相关抗氧化应激途径在足细胞中发挥抗衰老作用。随着近年来长寿研究的进展,酮体的有益作用逐渐被阐明,酮体的积极形象在包括肾病学在内的许多研究领域逐渐开始发展。

更新日期:2021-10-20
down
wechat
bug