Backgrounds. Individuals with hypertension are at higher risk of COVID-19 infection and related mortality. This study was carried out to assess the epidemiological features and predictors of mortality in patients with COVID-19 with hypertension. Methods. In this retrospective study, the epidemiological characteristics of two groups of patients with COVID-19 with hypertension (1927) and without hypertension (39030) were compared. Chi-square test was applied to evaluate the differences between qualitative variables in two study groups. Logistic regression was also used to determine predictors of mortality in patients with COVID-19 and in patients with COVID-19 with hypertension. Results. The prevalence of hypertension in patients with COVID-19 was 4.7%, and 24.37% of COVID-19 related deaths occurred in these individuals. The average age of hypertension and nonhypertension patients was 61 and 37 years, respectively. Fever, cough, headache, anorexia, fatigue, and comorbid diseases, such as cardiovascular disease, chronic lung and kidney disease, diabetes, immunodeficiency disease, and thyroid disease, were significantly more frequent in people with hypertension than those without hypertension. The chances of mortality in patient with COVID-19 were 1.8 times higher in individuals with dyspnea, 1.25 in individuals with fever, 1.33 in individuals with cough, 3.6 in patients with hypertension, 2.21 in diabetics, and 2.2 in individuals with cardiovascular disease. Also, individuals with COVID-19 with hypertension that had dyspnea, immunodeficiency, and cardiovascular disease were at higher risk of mortality. Conclusion. Hypertension is a serious threat to patients with COVID-19. Therefore, in order to control these patients more precisely and reduce mortality in them, it is extremely important to develop prevention and treatment strategies.

中文翻译：

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伴或不伴高血压的 COVID-19 患者的流行病学特征和死亡率预测因素


背景。高血压患者感染 COVID-19 和相关死亡的风险较高。本研究旨在评估患有高血压的 COVID-19 患者的流行病学特征和死亡率预测因素。方法。在这项回顾性研究中，比较了两组患有高血压的COVID-19患者（1927例）和不患有高血压的患者（39030例）的流行病学特征。应用卡方检验评估两个研究组中定性变量之间的差异。 Logistic 回归还用于确定 COVID-19 患者和患有高血压的 COVID-19 患者的死亡率预测因子。结果。 COVID-19 患者的高血压患病率为 4.7%，24.37% 的 COVID-19 相关死亡发生在这些个体中。高血压和非高血压患者的平均年龄分别为61岁和37岁。高血压患者出现发烧、咳嗽、头痛、厌食、疲劳以及心血管疾病、慢性肺肾疾病、糖尿病、免疫缺陷疾病和甲状腺疾病等合并症的频率明显高于非高血压患者。呼吸困难患者的 COVID-19 患者死亡率高出 1.8 倍，发烧患者的死亡率高出 1.25 倍，咳嗽患者的死亡率高出 1.33 倍，高血压患者的死亡率高出 3.6 倍，糖尿病患者的死亡率高出 2.21 倍，心血管疾病患者的死亡率高出 2.2 倍。此外，患有高血压、呼吸困难、免疫缺陷和心血管疾病的 COVID-19 患者的死亡风险较高。结论。高血压对 COVID-19 患者构成严重威胁。 因此，为了更精准地控制这些患者并降低其死亡率，制定预防和治疗策略极为重要。