Microbial removal of Chlortetracycline (CTC) at low CTC concentrations (in the order of 10–20 mg/L) has been reported. In this study, a novel microalgae-bacteria consortium was developed for effective CTC biodegradation at higher concentrations (up to 80 mg/L). The microalgae-bacteria consortium is resistant to up to 80 mg/L CTC, while the pure microalgal culture could only tolerate 60 mg/L CTC. CTC removal in the initial 12 h was primarily via biosorption by the microalgae-bacteria consortium and the adsorption capacity increased from 61.71 to 102.53 mg/g biomass in 12 h. Further, CTC biodegradation by the microalgae-bacteria consortium was catalyzed by extracellular enzymes secreted under antibiotic stress. The symbiotic bacterial diversity was analyzed by high throughput sequencing. The aerobic bacteria Porphyrobacter and Devosia were the dominant genera in the consortium. In the presence of CTC, a microbial community shift occurred with Chloroptast, Spingopyxis, and Brevundimonas being the dominant genera.

据报道，在低 CTC 浓度（大约 10-20 mg/L）下，微生物可以去除金霉素 (CTC)。在这项研究中，开发了一种新型微藻-细菌聚生体，用于在更高浓度（高达 80 mg/L）下进行有效的 CTC 生物降解。微藻-细菌联合体可耐受高达 80 mg/L 的 CTC，而纯微藻培养只能耐受 60 mg/L CTC。最初 12 小时的 CTC 去除主要是通过微藻-细菌聚生体的生物吸附进行的，吸附容量在 12 小时内从 61.71 增加到 102.53 毫克/克生物量。此外，微藻-细菌聚生体对 CTC 的生物降解是由在抗生素胁迫下分泌的细胞外酶催化的。通过高通量测序分析共生细菌多样性。好氧细菌Porphyrobacter和Devosia是该聚生体中的优势属。在CTC的存在，微生物群落发生移位与Chloroptast，Spingopyxis，以及短波单胞为优势属。