Integrin-mediated substrate-rigidity sensing triggers microtubule acetylation, modulating mechanosensitive cellular responses and focal adhesion dynamics, subsequently promoting actomyosin organization and collective cell migration.

中文翻译：

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微管介导的机械转导

整合素介导的底物刚性感应触发微管乙酰化，调节机械敏感细胞反应和粘着斑动力学，随后促进肌动球蛋白组织和集体细胞迁移。