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Normative blood pressure response to exercise stress testing in children and adolescents
Open Heart ( IF 2.8 ) Pub Date : 2021-10-01 , DOI: 10.1136/openhrt-2021-001807
Melanie M Clarke 1, 2 , Diana Zannino 3 , Natalie P Stewart 4 , Jonathan P Glenning 2, 4 , Salvador Pineda-Guevara 4 , Jolien Kik 5, 6 , Jonathan P Mynard 2, 4, 7 , Michael M H Cheung 2, 4, 5
Affiliation  

Objective To describe normative values for blood pressure (BP) response to maximal exercise in children/adolescents undergoing a treadmill stress test. Methods From a retrospective analysis of medical records, patients who had undergone a Bruce protocol exercise stress test, with (1) normal cardiovascular system and (2) a body mass index percentile rank below 95% were included for analysis. Sex, age, height, weight, resting and peak heart rate, resting and peak systolic blood pressure (SBP), test duration, stage of Bruce protocol at termination, reason for undergoing the test and reason for termination of test were collected. Percentiles for exercise-induced changes in SBP were constructed by age and height for each sex with the use of quantile regression models. Results 648 patients with a median age of 12.4 years (range 6–18 years) were included. Typical indications for stress testing were investigation of potential rhythm abnormalities, syncope/dizziness and chest pain and were deemed healthy by an overseeing cardiologist. Mean test duration was 12.6±2.2 min. Reference percentiles for change in SBP by sex, age and height are presented. Conclusion The presented reference percentiles for the change in SBP for normal children and adolescents will have utility for detecting abnormally high or low BP responses to exercise in these age groups. All data relevant to the study are included in the article or uploaded as supplemental information.

中文翻译:

儿童和青少年运动压力测试的正常血压反应

目的 描述接受跑步机压力测试的儿童/青少年最大运动量时血压 (BP) 反应的规范值。方法 通过对病历的回顾性分析,纳入接受布鲁斯方案运动压力测试、(1)心血管系统正常和(2)体重指数百分位数低于 95% 的患者进行分析。收集性别、年龄、身高、体重、静息和峰值心率、静息和峰值收缩压(SBP)、测试持续时间、终止时布鲁斯方案的阶段、接受测试的原因和终止测试的原因。使用分位数回归模型根据每个性别的年龄和身高构建运动引起的 SBP 变化的百分位数。结果 648 名患者中位年龄为 12.4 岁(范围 6-18 岁)。压力测试的典型适应症是调查潜在的节律异常、晕厥/头晕和胸痛,并被一名监督心脏病专家认为是健康的。平均测试持续时间为 12.6±2.2 分钟。提供了按性别、年龄和身高变化的 SBP 变化的参考百分位数。结论 所呈现的正常儿童和青少年 SBP 变化的参考百分位数可用于检测这些年龄组对运动的异常高或低 BP 反应。所有与研究相关的数据都包含在文章中或作为补充信息上传。提供了按性别、年龄和身高变化的 SBP 变化的参考百分位数。结论 所呈现的正常儿童和青少年 SBP 变化的参考百分位数可用于检测这些年龄组对运动的异常高或低 BP 反应。所有与研究相关的数据都包含在文章中或作为补充信息上传。提供了按性别、年龄和身高变化的 SBP 变化的参考百分位数。结论 所呈现的正常儿童和青少年 SBP 变化的参考百分位数可用于检测这些年龄组对运动的异常高或低 BP 反应。所有与研究相关的数据都包含在文章中或作为补充信息上传。
更新日期:2021-10-19
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