Is Chemotherapy Associated with Improved Overall Survival in Patients with Dedifferentiated Chondrosarcoma? A SEER Database Analysis.,Clinical Orthopaedics and Related Research

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Is Chemotherapy Associated with Improved Overall Survival in Patients with Dedifferentiated Chondrosarcoma? A SEER Database Analysis.
Clinical Orthopaedics and Related Research ( IF 4.2 ) Pub Date : 2021-10-14 , DOI: 10.1097/corr.0000000000002011
Lee D Cranmer _{1,

2} , Bonny Chau ₁ , Jose G Mantilla ₃ , Elizabeth T Loggers _{1,

2} , Seth M Pollack _{1,

2} , Teresa S Kim ₄ , Edward Y Kim ₅ , Gabrielle M Kane ₅ , Matthew J Thompson ₆ , Jared L Harwood ₆ , Michael J Wagner _{1,

2}

Affiliation

Dedifferentiated chondrosarcoma is a chondrosarcoma subtype associated with high rates of recurrence and a poor prognosis. Others have proposed treatment of dedifferentiated chondrosarcoma using osteosarcoma protocols, including perioperative chemotherapy. However, the rarity of this condition poses difficulties in undertaking single- institution studies of sufficient sample size.

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