Huntington’s disease (HD) is a dramatic neurodegenerative disorder encompassing severe motor symptoms coupled to significant cognitive and social cognition deficits. However, it is not clear whether and how patients’ neuropsychological profile changes between the prodromal and the manifest stages of the condition. The aim of the present in-depth review is to consider cognitive and social cognition impairment in HD patients by differentiating deficits arising before diagnosis from those evident from the manifest phase onwards.

中文翻译：

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亨廷顿病的认知和社会认知缺陷在疾病的前驱期和表现期之间有所不同：对最近证据的范围审查

亨廷顿舞蹈病 (HD) 是一种剧烈的神经退行性疾病，包括严重的运动症状以及显着的认知和社会认知缺陷。然而，尚不清楚患者的神经心理学特征是否以及如何在疾病的前驱期和表现期之间发生变化。本深入综述的目的是通过区分诊断前出现的缺陷与从明显阶段开始的明显缺陷来考虑 HD 患者的认知和社会认知障碍。