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Imaging of iris vasculature: current limitations and future perspective
Eye ( IF 2.8 ) Pub Date : 2021-10-14 , DOI: 10.1038/s41433-021-01809-2
Claudio Iovino 1 , Enrico Peiretti 2 , Mirco Braghiroli 2 , Filippo Tatti 2 , Abhilasha Aloney 3 , Michele Lanza 1 , Jay Chhablani 4
Affiliation  

Fluorescein and indocyanine green angiography have been the traditional ways to image the vasculature of the iris in the last few decades. Because of the invasive nature of these procedures, they are performed in rare situations, and thus, our understanding about iris vasculature is very limited. Optical coherence tomography angiography (OCTA) is a noninvasive imaging method that enables the detailed visualization of the retinal and choroidal vascular networks. More recently, it has been also used for the examination of the iris vasculature in healthy and disease eyes. However, there is a lack of uniformity in the image acquisition protocols and interpretations in both healthy and pathological conditions. Artifacts of iris OCTA include shadowing, motion, segmentations errors, mirror effects. OCTA devices have an eye-tracking system designed for the posterior segment and the applications of these systems on the anterior segment can determine motion lines, vessel duplication, and vessel discontinuity. OCTA of the iris should always be performed under ambient room lighting to create miosis and reduce iris vasculature changes during the examination. In the near future, eye-tracking systems specifically designed for the iris vessels could permit the follow-up function, and the development of new OCTA metrics could reveal interesting applications of this new imaging technique.



中文翻译:

虹膜血管成像:当前局限性和未来前景

在过去的几十年里,荧光素和吲哚菁绿血管造影术一直是虹膜脉管系统成像的传统方法。由于这些手术的侵入性,它们只在极少数情况下进行,因此,我们对虹膜血管系统的了解非常有限。光学相干断层扫描血管造影 (OCTA) 是一种无创成像方法,可以详细显示视网膜和脉络膜血管网络。最近,它还被用于检查健康眼和疾病眼的虹膜脉管系统。然而,在健康和病理条件下,图像采集协议和解释都缺乏统一性。虹膜 OCTA 的伪影包括阴影、运动、分割错误、镜像效应。OCTA 设备具有专为眼后段设计的眼动追踪系统,这些系统在眼前段的应用可以确定运动线、血管重复和血管不连续性。虹膜 OCTA 应始终在环境室内照明下进行,以产生瞳孔缩小并减少检查期间虹膜血管的变化。在不久的将来,专为虹膜血管设计的眼动追踪系统可以实现后续功能,新 OCTA 指标的开发可以揭示这种新成像技术的有趣应用。虹膜 OCTA 应始终在环境室内照明下进行,以产生瞳孔缩小并减少检查期间虹膜血管的变化。在不久的将来,专为虹膜血管设计的眼动追踪系统可以实现后续功能,新 OCTA 指标的开发可以揭示这种新成像技术的有趣应用。虹膜 OCTA 应始终在环境室内照明下进行,以产生瞳孔缩小并减少检查期间虹膜血管的变化。在不久的将来,专为虹膜血管设计的眼动追踪系统可以实现后续功能,新 OCTA 指标的开发可以揭示这种新成像技术的有趣应用。

更新日期:2021-10-14
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