Chiral Phosphoric Acids as Versatile Tools for Organocatalytic Asymmetric Transfer Hydrogenations,European Journal of Organic Chemistry

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Chiral Phosphoric Acids as Versatile Tools for Organocatalytic Asymmetric Transfer Hydrogenations
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2021-10-14 , DOI: 10.1002/ejoc.202100894
Ádám Márk Pálvölgyi ₁ , Fabian Scharinger ₁ , Michael Schnürch ₁ , Katharina Bica-Schröder ₁

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Organocatalytic asymmetric transfer hydrogenation provides a metal-free and ambient alternative to classical reductions. Chiral phosphoric acid-catalysis represents a powerful strategy in this field, with a range of novel and selective methods for various double bond reductions. This Minireview provides an overview on recent advances including the effect of different phosphoric acids and reductants.