To explore the potential relevance of muscle mass as a variable contributor to BMI in limitations on BMI-based predictions of diabetes remission (DR) after Roux-en-Y gastric bypass (RYGB).

We evaluated the relationship between muscle mass and BMI in 501 patients with type 2 diabetes mellitus and overweight or obesity, of whom 186 patients who underwent RYGB were studied for determination of the role of baseline muscle mass and BMI in predicting DR. Muscle mass was assessed by estimated fat-free mass index (eFFMI) and psoas cross-sectional area (CSA).

A nonlinear relationship existed between psoas CSA and BMI, whereas psoas CSA showed a highly positive correlation with eFFMI. Baseline psoas CSA and eFFMI were better than BMI for predicting 1- and 5-year DR.

The nonlinear relationship between muscle mass and BMI may partially contribute to BMI limitations in predicting DR after RYGB.

探索肌肉质量作为 BMI 的一个变量因素的潜在相关性，以限制基于 BMI 的 Roux-en-Y 胃旁路手术 (RYGB) 后糖尿病缓解 (DR) 的预测。

我们评估了 501 名 2 型糖尿病和超重或肥胖患者的肌肉质量和 BMI 之间的关系，其中研究了 186 名接受 RYGB 的患者，以确定基线肌肉质量和 BMI 在预测 DR 中的作用。通过估计的无脂肪质量指数 (eFFMI) 和腰大肌横截面积 (CSA) 评估肌肉质量。

psoas CSA 与 BMI 之间存在非线性关系，而 psoas CSA 与 eFFMI 呈高度正相关。基线腰大肌 CSA 和 eFFMI 在预测 1 年和 5 年 DR 方面优于 BMI。

肌肉质量和 BMI 之间的非线性关系可能部分导致 BMI 在预测 RYGB 后 DR 方面的局限性。