ABSTRACT

Purpose

To describe the clinical characteristics, severity, and ophthalmological changes in SARS-CoV-2 patients through ophthalmological examinations performed at the reference center of the National Institute of Infectious Diseases, Brazil.

Methods

This cross-sectional study assessed the examination results of SARS-CoV-2 patients from July 2020 to November 2020. In total, 150 patients were included and allocated into three groups of 50 patients depending on the disease severity. Group 1 patients were in the intensive care unit (ICU), group 2 patients were in the semi-ICU, and group 3 patients were outpatients.

Results

Ten (6.7%) patients exhibited ophthalmological changes; five (10%), four (8%), and one (2%) patients in groups 1, 2, and 3, respectively. Ophthalmological findings included candle flame hemorrhage and cotton wool exudates. We analyzed the general characteristics of the 10 patients with ophthalmological changes. Nine were hospitalized and one was seen on an outpatient basis.

Conclusion

We observed ophthalmic changes in patients with SARS-CoV-2 infection, despite the absence of any clinical or laboratory risk factors indicative of such changes.

中文翻译：

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在国家传染病研究所检查的 SARS-CoV-2 感染患者的眼科检查结果 - INI/Fiocruz

摘要

目的

通过在巴西国家传染病研究所参考中心进行的眼科检查，描述 SARS-CoV-2 患者的临床特征、严重程度和眼科变化。

方法

这项横断面研究评估了 2020 年 7 月至 2020 年 11 月 SARS-CoV-2 患者的检查结果。总共纳入了 150 名患者，并根据疾病严重程度将其分为三组，每组 50 名患者。第 1 组患者在重症监护室 (ICU)，第 2 组患者在半 ICU，第 3 组患者在门诊。

结果

十名 (6.7%) 患者表现出眼科变化；第 1、2 和 3 组分别有 5 名 (10%)、4 名 (8%) 和 1 名 (2%) 患者。眼科检查结果包括烛焰出血和脱脂棉渗出物。我们分析了 10 名眼科变化患者的一般特征。9 人住院，1 人在门诊就诊。

结论

我们观察了 SARS-CoV-2 感染患者的眼部变化，尽管没有任何临床或实验室风险因素表明此类变化。