ABSTRACT

The novel pandemic coronavirus disease 2019 (COVID-19) leading to health and economic problems worldwide is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although COVID-19 mainly occurs as a lower respiratory tract infection, there is multiorgan involvement in infected patients. The disease is transmitted from person to person through air droplets or contact with contaminated surfaces. SARS-CoV-2 leads to this systemic involvement by attaching to angiotensin-converting enzyme 2 (ACE2) receptors located on several human cells. Since SARS-CoV-2 RNA has been found in tears of infected patients, ocular surface may allow the virus to transmit to nasopharynx via the nasolacrimal duct. This narrative review aims to sum up all segmental ocular complications, ocular adverse effects of COVID-19 treatment, and preventive measures suggested to minimize the SARS-CoV-2 transmission between patients and ophthalmologists by reviewing currently available literature.

摘要

导致全球健康和经济问题的新型大流行冠状病毒病 2019 (COVID-19) 是由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 引起的。尽管 COVID-19 主要作为下呼吸道感染发生，但受感染的患者有多个器官受累。该疾病通过空气飞沫或接触受污染的表面在人与人之间传播。SARS-CoV-2 通过附着在几个人体细胞上的血管紧张素转换酶 2 (ACE2) 受体上而导致这种全身性参与。由于在感染患者的眼泪中发现了 SARS-CoV-2 RNA，因此眼表可能使病毒通过鼻泪管传播到鼻咽部。这篇叙述性综述旨在总结 COVID-19 治疗的所有节段性眼部并发症、眼部不良反应、