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Statistical Significance vs Clinical Significance—That Is the Question
JAMA Ophthalmology ( IF 7.8 ) Pub Date : 2021-11-01 , DOI: 10.1001/jamaophthalmol.2021.4139
Jennifer Rose-Nussbaumer 1, 2
Affiliation  

Microincision cataract surgery, defined as wounds of around 2 mm or smaller, have been shown to reduce surgically induced astigmatism compared with small-incision cataract surgery wounds of 3 mm or greater.1 Therefore, cataract surgeons have intuitively concluded that the smaller the wound, the better, with regard to wound stability and topographic neutrality. However, 2.2-mm incisions have been shown to increase small Descemet membrane detachments (DMD) on postoperative day 1 compared with 2.85-mm incisions and, in 1 study, these detachments translated into slower visual recovery for patients.2



中文翻译:

统计学意义与临床意义——这是个问题

与 3 毫米或更大的小切口白内障手术伤口相比,微切口白内障手术(定义为大约 2 毫米或更小的伤口)已被证明可以减少手术引起的散光。1因此,白内障外科医生直观地得出结论,在伤口稳定性和地形中性方面,伤口越小越好。然而,与 2.85 毫米切口相比,2.2 毫米切口已显示在术后第 1 天会增加小后弹力膜脱离 (DMD),并且在 1 项研究中,这些脱离会导致患者的视力恢复较慢。2

更新日期:2021-11-17
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